By American Academy of Ophthalmology, Robert H. Rosa Jr. MD
Part four offers fabrics in elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific elements. half I makes use of a hierarchy that strikes from basic to precise to assist derive a differential prognosis for a particular tissue. half II is a compilation of chosen scientific points of value to the final ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging kinds for ocular and adnexal tumors.
Upon of completion of part four, readers will be capable to:
Describe a dependent method of realizing significant ocular stipulations in accordance with a hierarchical framework of topography, sickness technique, common prognosis and differential diagnosis
Summarize the stairs in dealing with ocular specimens for pathologic examine, together with acquiring, dissecting, processing, and marking tissues
Identify these ophthalmic lesions that point out systemic ailment and are in all likelihood existence threatening
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Additional info for 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors
Thus, molecular genetics has already become an integral part of the workup of tumors, such as pediatric orbital tumors (rhabdomyosarcomas, CHAPTER 4: Special Procedures • 43 ,, ·oblastoma , peripheral neuroectodermal tumors [PNET]), that demonstrate charnew . teristic translocations. Based on the results, treatment can be directed and prognostic ,lC . I1 certam . J.. • d 1 . features associate d wit an trans ocat10ns. Hicks J, Mierau GW. The spectrum of pediatric tumors in infancy, childhood, and adolescence: a comprehensive review with emphasis on special techniques in diagnosis.
Frozen sect10ns are a t1me-mtens1ve and costly p rocess and hould be used with discretion. It is considered inappropriate to order frozen sections and then to proceed with a case before receiving the results from the pathologist. To ensure adequate understanding of the case and facilitate the best possible results for the patient, the surgeon should communicate with the pathologist ahead of time if a frozen section is anticipated. Chevez-Barrios P. Frozen section diagnosis and indications in ophthalmic pathology.
In an ulcer, the surface is covered by epithelium, but little of the lost stroma is replaced by fibrous tissue. Modification of the healing process by use of topical antimetabolites, such as 5-fluorouracil and mitomycin C, may be desirable in certain clinical situations (see BCSC Section 10, Glaucoma, Chapter 8). Sciera The sclera differs from the cornea in that the collagen fibers are randomly distributed rather than laid down in orderly lamellae, and the glycosaminoglycan is dermatan sulfate.
2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors by American Academy of Ophthalmology, Robert H. Rosa Jr. MD